Guhindura Ibikoresho | N / A. |
Cas No. | 71963-77-4 |
Imiti yimiti | C16H26O5 |
Uburemere bwa molekile | 298.37 |
EINECS oya. | 663-549-0 |
Ingingo yo gushonga | 86-88 ° C. |
Ingingo yo guteka | 359.79 ° C (igereranya) |
Kuzenguruka byihariye | D19.5 + 171 ° (c = 2.59inCHCl3) |
Ubucucike | 1.0733 (igereranya) |
Ironderero ryo kugabanuka | 1.6200 (igereranya) |
Imiterere yo kubika | Icyumba temp |
Gukemura | DMSO≥20mg / mL |
Kugaragara | Ifu |
Synonyme | Artemetherum / Artemtherin / Dihydroartemisininmethylether |
Gukemura | Kubora mumazi |
Ibyiciro | Ibimera bivamo, Inyongera, Ubuvuzi |
Porogaramu | Kurwanya malariya |
Artemether ni sesquiterpene lactone iboneka mumuzi yaArtemisia annua, bizwi cyane nk'inzoka nziza. Numuti ukomeye wa antimalarial ukoreshwa mukuvura no gukumira malariya. Artemisinin, uwabanjirije byose, yakuwe bwa mbere muri urwo ruganda mu myaka ya za 70, kandi ivumburwa ryayo ryabonye umushakashatsi w’umushinwa Tu Youyou igihembo cyitiriwe Nobel mu buvuzi mu 2015.
Artemether ikora mukurimbura parasite ishinzwe gutera malariya. Malariya iterwa na parasite ya protozoan yitwa Plasmodium, yanduza abantu binyuze mu kurumwa n'imibu ya Anopheles yanduye. Iyo parasite imaze kwinjira mumuntu yakira, parasite igwira vuba mumwijima no mumaraso atukura, bigatera umuriro, gukonja, nibindi bimenyetso bisa nibicurane. Iyo itavuwe, malariya irashobora guhitana abantu.
Artemether ifite akamaro kanini mukurwanya imiti ya Plasmodium falciparum, niyo ihitana abantu benshi bapfa bazize malariya kwisi yose. Ifite kandi akamaro ubundi bwoko bwa parasite ya Plasmodium itera malariya. Ubusanzwe Artemether itangwa ifatanije nibindi biyobyabwenge, nka lumefantrine, kugirango bigabanye ibyago byo kurwanya ibiyobyabwenge.
Usibye kuba ikoreshwa nk'imiti igabanya ubukana, hamwe na hamwe wasangaga ifite ubundi buryo bwo kuvura. Ubushakashatsi bwerekanye ko bufite ibikorwa byo kurwanya inflammatory, kurwanya ibibyimba, no kurwanya virusi. Yakoreshejwe mu kuvura indwara ya rubagimpande, lupus, nizindi ndwara ziterwa na autoimmune. Hakozwe kandi ubushakashatsi ku bushobozi bwo kuvura COVID-19, nubwo hakenewe ubushakashatsi bwinshi kugira ngo hemezwe neza.
Artemether muri rusange ifite umutekano kandi yihanganirwa neza iyo ikoreshejwe nkuko byateganijwe. Ariko, kimwe nibiyobyabwenge byose, birashobora gutera ingaruka. Ingaruka zikunze kugaragara cyane zirimo isesemi, kuruka, kuzunguruka, no kubabara umutwe. Mubihe bidakunze kubaho, birashobora gutera ingaruka zikomeye, nko guhagarika umutima, gufatwa, no kwangiza umwijima.
Mu gusoza, byose hamwe ni imiti ikomeye ya antimalariya yahinduye imiti ya malariya no kuyirinda. Ivumburwa ryarokoye ubuzima butabarika kandi ryamenyekanye mubumenyi bwa siyanse. Ibindi bikoresho byo kuvura bituma iba umukandida utanga ikizere cyo kuvura izindi ndwara. Nubwo ishobora gutera ingaruka, inyungu zayo ziruta kure ingaruka zayo iyo ikoreshejwe mugenzurwa nubuvuzi.
Ifishi ikoreshwa cyane irimo ibinini, capsules hamwe ninshinge. Ubwoko bw'ibiyobyabwenge ni imiti igabanya ubukana, kandi ibyingenzi ni byose hamwe. Imiterere itera ibinini byose byari ibinini byera. Imiterere ya artemether capsule ni capsule, ibiyirimo ni ifu yera; Ibiyobyabwenge biranga inshinge zose ntizifite ibara ryamavuta yumuhondo yoroheje - nkamazi.
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