Imyitwarire y'abaguzi ku gusaza iragenda ihinduka. Ukurikije raporo yerekana abaguzi raporo yaUmuguzi mushyanaUmurwa mukuru, Abanyamerika benshi ntibibanda ku kuramba gusa ahubwo no kwibanda ku mibereho myiza.
Ubushakashatsi bwakozwe na 2024 bwakozwe na McKinsey bwerekanye ko mu mwaka ushize, 70% by’abaguzi muri Amerika no mu Bwongereza (na 85% mu Bushinwa) baguze ibicuruzwa na serivisi byinshi bifasha gusaza neza no kuramba ugereranije n’imyaka yashize. Ihinduka ryerekana ubushake bwabaguzi bwo gufata neza ubuzima bwabo.
Byongeye kandi,Imirire yubucuruzi Ikinyamakuru(NBJ) 2024 Raporo yo kuramba yerekana ko kuva mu 2022, ubwiyongere bw’igurisha mu cyiciro cyiza cyo gusaza bwakomeje gusumba isoko ryinyongera ryagutse. Muri 2023, inganda ziyongera muri rusange ziyongereyeho 4.4%, mugihe icyiciro cyiza cyo gusaza cyageze ku kigero cya 5.5%.NBJimishinga igurisha inyongeramusaruro nziza yubusaza-ikubiyemo ibyiciro bitandukanye byihariye-izarenga miliyari imwe y'amadolari muri 2024 ikagera kuri miliyari 1.04 muri 2026, bivuze ko izamuka rya 7.7%.
Abaguzi bahangayikishijwe nibibazo byubuzima bijyanye nimyaka
AnNBJubushakashatsi bwakozwe mu 2024 bwerekanye ibibazo by’abaguzi bijyanye no gusaza. Ibibazo by'ingenzi birimo:
Gutakaza kugenda (28%)
Indwara ya Alzheimer cyangwa guta umutwe (23%)
Gutakaza icyerekezo (23%)
Gutakaza ubwigenge (19%)
Ibibazo byubuzima bwamarangamutima cyangwa mumutwe (19%)
Kwangirika kw'imitsi cyangwa skelete (19%)
Gutakaza umusatsi (16%)
Gusinzira (16%)
Inkomoko y'amashusho: NBJ
Iyo ukoresheje inyongeramusaruro, ubudahangarwa (35%) bwagaragaye nkibibazo byingenzi byubuzima bijyanye nimyaka kubaguzi. Ibindi byashyizwe imbere harimo amara nubuzima bwigifu (28%), ubuzima bwibitotsi (23%), umusatsi, uruhu, n imisumari (22%), imitsi nubuzima bufatanye (21%), ubuzima bwumutima (19%), no kumererwa neza mumarangamutima (19%).
Inkomoko y'amashusho: NBJ
Ibintu bitanu byingenzi birwanya gusaza
1. Ergothioneine
Ergothioneine ni aside isanzwe iboneka muri 1909 na Charles Tanret igihe yiga ibihumyo bya ergot. Umwihariko wa thiol na thione tautomerism kuri physiologique pH itanga imiterere idasanzwe ya antioxydeant. Dukurikije amakuru yaturutse muri Bloomage Biotech, ergothioneine muri Bioyouth ™ -EGT yerekana ibikorwa bya DPPH byubusa bikabije inshuro 14 bya glutathione ninshuro 30 bya coenzyme Q10.
Inyungu:
Uruhu:Ergothioneine irinda umuriro uterwa na UV, irinda kwangirika kwa ADN, kandi igatera synthesis ya kolagen mugihe igabanya kwangirika kwa UV.
Ubwonko:Ergothioneine ishyigikira imikorere yubwenge, nkuko bigaragazwa nubushakashatsi bwamavuriro bwerekana ubumenyi bunoze nyuma yibyumweru 12 byuzuzanya na ergothioneine ikomoka ku bihumyo.
Sinzira:Irenga inzitizi yamaraso-ubwonko, igabanya imiterere ya peroxynitrite, kandi igabanya imihangayiko, itera gusinzira neza.
2. Spermidine
Spermidine, igice cyumuryango wa polyamine, iboneka cyane mubinyabuzima nka bagiteri, ibihumyo, ibimera, ninyamaswa. Inkomoko y'ibiryo ikubiyemo mikorobe y'ingano, soya, n'ibihumyo bya king oyster. Urwego rwa spermidine rugabanuka uko imyaka igenda ishira, kandi ingaruka zayo zo kurwanya gusaza ziterwa nuburyo bukoreshwa nka autofagy induction, ibikorwa byo kurwanya inflammatory, hamwe na lipide metabolism.
Uburyo:
Autophagy:Spermidine iteza imbere ingirabuzimafatizo, ikemura indwara ziterwa n'imyaka ifitanye isano na autofagy.
Kurwanya inflammatory: Igabanya cytokine itera inflammatory mugihe yongera ibintu birwanya inflammatory.
Lipid Metabolism:Spermidine igira ingaruka nziza kuri synthesis ya lipid no kubika, igafasha ingirabuzimafatizo ya selile no kuramba.
3. Pyrroloquinoline Quinone (PQQ)
PQQ, amazi ya elegitoronike ya quinone coenzyme, ni ingenzi kumikorere ya mito-iyambere. Irinda okiside itera imbaraga ziterwa na mitochondial yangiza, itera biogenezi ya mitochondial, kandi ikongera imbaraga zo gukura kwimitsi (NGF). Ubuvuzi bwa Clinical bwerekana akamaro kabwo mugutezimbere imikorere yubwenge no gutembera kwamaraso mukarere kubantu bageze mu zabukuru.
4. Fosifatiidylserine (PS)
PS ni anionic fosifolipide muri selile ya eukaryotic, ingenzi mubikorwa nko gukora enzyme, selile apoptose, hamwe nibikorwa bya synaptic. PS ikomoka ku masoko nka soya, ibinyabuzima byo mu nyanja, hamwe n’izuba, PS ishyigikira sisitemu ya neurotransmitter, harimo acetylcholine na dopamine, bifitanye isano nubuzima bwubwenge.
Porogaramu:Kwiyongera kwa PS bifitanye isano no gutera imbere mubihe nka Alzheimer, indwara ya Parkinson, no kwiheba, kandi bigirira akamaro abantu barwaye ADHD na autism.
5. Urolithin A (UA)
UA, metabolite ya ellagitannine iboneka mu biribwa nk'amakomamanga na ياڭ u, byagaragaye mu 2005. Ubushakashatsi bwasohotse muriUbuvuzi bwa Kamere(2016) yerekanye ko UA iteza imbere mitofagy, ikongerera igihe cya nematode 45%. Ikora inzira ya mitochondrial autophagy, ikuraho mitochondriya yangiritse kandi ikemura ibibazo biterwa nimyaka mumitsi, imitsi yumutima, ubudahangarwa, nubuzima bwuruhu.
UA yakoresheje mitofagy inzira / Ishusho yinkomoko 1
Umwanzuro
Mugihe abaguzi bagenda bashira imbere ubuzima no kuramba, icyifuzo cyibintu bishya birwanya gusaza nibindi byiyongera bikomeje kwiyongera. Ibyingenzi byingenzi nka ergothioneine, spermidine, PQQ, PS, na UA biratanga inzira kubisubizo bigamije gukemura ibibazo bijyanye nimyaka. Ibi bikoresho bishyigikiwe na siyansi bishimangira inganda ziyemeje gushyigikira gusaza ubuzima bwiza, kandi bukomeye.
Igihe cyo kohereza: Mutarama-08-2025