Astaxanthin (3,3'-dihydroxy-beta, beta-carotene-4,4'-dione) ni carotenoid, ishyirwa mu cyiciro cya lutein, iboneka mu dukoko twinshi dutandukanye n'inyamaswa zo mu mazi, kandi yakuwe mu dukoko na Kuhn na Sorensen. Ni ibara rishongesha ibinure rigaragara nk'umuhondo cyangwa umutuku wijimye kandi ridafite Vitamine A mu mubiri w'umuntu.
Astaxanthin ikomoka ku bimera karemano birimo algae, umusemburo, salmon, trout, krill na crayfish. Astaxanthin ikomoka ahanini ku musemburo wa Fife, algae itukura ndetse no mu mikorere ya shimi. Imwe mu masoko meza ya astaxanthin karemano ni chlorella itukura iterwa n'imvura, ifite astaxanthin ingana na 3.8% (ku buremere bwumye), kandi salmon yo mu gasozi nayo ni isoko nziza ya astaxanthin. Umusaruro w'ubukorikori uracyari isoko nyamukuru ya astaxanthin bitewe n'igiciro kinini cyo guhinga Rhodococcus rainieri. Imikorere ya astaxanthin ikomoka ku bimera igizwe na 50% gusa by'iya astaxanthin karemano.
Astaxanthin iboneka nk'ibice by'ibara rya stereoisomer, ibice by'ibara rya geometrike, imiterere yigenga n'iy'ibara rya ester, aho ibice by'ibara rya stereoisomer (3S,3'S) na (3R,3'R) ari byo byinshi mu miterere yabyo. Rhodococcus rainieri ikora ibice by'ibara rya (3S,3'S) naho umusemburo wa Fife ugakora ibice by'ibara rya (3R,3'R).
Astaxanthin, ubushyuhe bw'igihe gito
Astaxanthin ni ingenzi mu biribwa bikora neza mu Buyapani. Imibare ya FTA ku byatangajwe mu Buyapani mu 2022 yagaragaje ko astaxanthin yari ku mwanya wa 7 mu bintu 10 bya mbere mu bijyanye n'inshuro ikoreshwa, kandi yakoreshejwe cyane cyane mu rwego rw'ubuzima nko kwita ku ruhu, kwita ku maso, kugabanya umunaniro, no kunoza imikorere y'ubwonko.
Mu bihembo bya 2022 na 2023 by’ibikomoka ku mirire byo muri Aziya,Ubuzima bwa Justgood Ikinyabutabire cya astaxanthin karemano cyamenyekanye nk'ikintu cyiza cyane mu mwaka mu myaka ibiri yikurikiranya, ikintu cyiza cyane mu buryo bwo gutekereza mu 2022, ndetse n'ikintu cyiza cyane mu buryo bwo kwita ku bwiza mu kanwa mu 2023. Byongeye kandi, iki kintu cyashyizwe ku rutonde rw'ibitaramo bya Asian Nutritional Ingredients Awards - Healthy Aging Awards mu 2024.
Mu myaka ya vuba aha, ubushakashatsi ku bushakashatsi kuri astaxanthin nabwo bwatangiye gushyuha. Dukurikije amakuru ya PubMed, kuva mu 1948, habayeho ubushakashatsi kuri astaxanthin, ariko ubwitabire bwari buke, guhera mu 2011, amashuri makuru yatangiye kwibanda kuri astaxanthin, aho ibitabo birenga 100 byasohotse buri mwaka, naho ibirenga 200 muri 2017, ibirenga 300 muri 2020, n'ibirenga 400 muri 2021.
Inkomoko y'ifoto: PubMed
Ku bijyanye n'isoko, nk'uko bigaragara ku isoko rya Future, ingano y'isoko ry'isi ya astaxanthin iteganijwe kuba miliyoni 273.2 z'amadolari y'Amerika mu 2024 kandi biteganijwe ko izagera kuri miliyoni 665.0 z'amadolari y'Amerika mu 2034, ku kigero cya CAGR cya 9.3% mu gihe cy'iteganyagihe (2024-2034).
Ubushobozi bwo kurwanya antioxidant buri hejuru cyane
Imiterere yihariye ya Astaxanthin iha ubushobozi buhebuje bwo kurwanya antioxidant. Astaxanthin irimo imigozi ibiri yahuje, hydroxyl na ketone groups, kandi ikunda lipophilic na hydrophilic. Imigozi ibiri yahuje iri hagati muri icyo kinyabutabire itanga electron kandi igakorana na free radicals kugira ngo ihindurwemo ibintu bihamye kandi bihagarike free radical chain reactions mu binyabuzima bitandukanye. Imikorere yayo y’ibinyabuzima iruta iy’izindi antioxidant bitewe n’ubushobozi bwayo bwo guhuza n’uturemangingo tw’uturemangingo uhereye imbere ugana inyuma.
Aho astaxanthin n'izindi antioxydants ziri mu ngirabuzimafatizo
Astaxanthin igira uruhare runini mu kurwanya imisemburo mibi, atari mu gusa gukuraho imisemburo mibi mu buryo butaziguye, ahubwo no mu gukora uburyo bwo kurinda utunyangingo tw’uturemangingo binyuze mu kugenzura inzira ya nuclear factor erythroid 2-related factor (Nrf2). Astaxanthin ibuza ikorwa rya ROS kandi ikagenzura uburyo imisemburo irwanya imisemburo mibi, nka heme oxygenase-1 (HO-1), ikaba ari ikimenyetso cy’ihungabana ry’imisemburo mibi.HO-1 igenzurwa n’ibintu bitandukanye birwanya ihungabana, harimo na Nrf2, ihuza n’ibintu birwanya imisemburo mibi mu gace gatera imbaraga imisemburo mibi.
Urusobe rwuzuye rw'inyungu za astaxanthin n'ikoreshwa ryayo
1) Kunoza imikorere y'ubwonko
Ubushakashatsi bwinshi bwemeje ko astaxanthin ishobora gutinza cyangwa kongera ubushobozi bwo gutekereza bujyanye no gusaza bisanzwe cyangwa ikagabanya indwara zitandukanye ziterwa no kwangirika kw'imitsi. Astaxanthin ishobora kwambuka umupaka w'amaraso n'ubwonko, kandi ubushakashatsi bwagaragaje ko astaxanthin ikomoka ku mirire yirundanya muri hippocampus na cortex y'ubwonko bw'imbeba nyuma yo kuyinywa rimwe gusa kandi inshuro nyinshi, ibi bishobora kugira ingaruka ku mikorere y'ubwonko. Astaxanthin itera imbere mu kongera ireme ry'uturemangingo tw'imitsi kandi yongera imiterere ya gene ya glial fibrillary acidic protein (GFAP), microtubule-associated protein 2 (MAP-2), brain-derived neurotrophic factor (BDNF), na growth-associated protein 43 (GAP-43), poroteyine zigira uruhare mu kugarura ubwonko.
Udupira twa Justgood Health Astaxanthin, hamwe na Cytisine na Astaxanthin biva mu ishyamba ry’inzitane ry’umukara, birakorana kugira ngo binoze imikorere y’ubwonko mu bwenge.
2) Uburinzi bw'amaso
Astaxanthin ifite imikorere ya antioxydant igabanya ubukana bw'uturemangingo tw’ingufu zidafite umwuka wa ogisijeni kandi igatanga uburinzi ku maso. Astaxanthin ikorana neza n'izindi carotenoide zifasha ubuzima bw'amaso, cyane cyane lutein na zeaxanthin. Byongeye kandi, astaxanthin yongera umuvuduko w'amaraso mu jisho, bigatuma amaraso yongera ogisijeni muri retina no mu ngirabuzima fatizo z'amaso. Ubushakashatsi bwagaragaje ko astaxanthin, hamwe n'izindi carotenoide, irinda amaso kwangirika mu mirasire y'izuba. Byongeye kandi, astaxanthin ifasha mu kugabanya ububabare bw'amaso no kunanirwa kureba.
Ibikoresho by'ingenzi: lutein, zeaxanthin, astaxanthin, Justgood Health Blue Light Protection Softgels.
3) Kwita ku ruhu
Imihangayiko ya okisidatike ni ikintu cy'ingenzi gituma uruhu rw'umuntu rusaza ndetse n'uruhu rwangirika. Uburyo bwo gusaza kw'imbere mu mubiri (kw'igihe) no hanze (kw'urumuri) ni ukubyara ROS, mu buryo bw'umubiri binyuze mu mikorere ya okisidatike, ndetse no hanze yayo binyuze mu kwibasirwa n'imirasire y'izuba ya ultraviolet (UV). Ibintu bitera okisidatike mu gusaza kw'uruhu birimo kwangirika kwa ADN, kwitwara mu bubyimba, kugabanuka kwa okisidatike, no gukora matrix metalloproteinases (MMPs) zangiza kolajeni na elastine mu mubiri.
Astaxanthin ishobora gukumira neza kwangirika kwa okisideri iterwa na radicals yigenga ndetse no kwinjiza MMP-1 mu ruhu nyuma yo kwibasirwa n'imirasire ya UV. Ubushakashatsi bwagaragaje ko astaxanthin ikomoka kuri Erythrocystis rainbowensis ishobora kongera collagen ibuza MMP-1 na MMP-3 gukora mu mikurire y'uruhu rw'umuntu. Byongeye kandi, astaxanthin yagabanyije kwangirika kwa ADN iterwa na UV ndetse yongera uburyo ADN isana mu turemangingo twahuye n'imirasire ya UV.
Justgood Health ubu irimo gukora ubushakashatsi butandukanye, burimo imbeba zitagira ubwoya n'igerageza ku bantu, byose byagaragaje ko astaxanthin igabanya kwangirika kwa UV ku bice byimbitse by'uruhu, bigatera ibimenyetso by'uko uruhu rusaza, nko kuma, uruhu rurenduka ndetse n'iminkanyari.
4) Indyo ya siporo
Astaxanthin ishobora kwihutisha gusana nyuma yo gukora imyitozo ngororamubiri. Iyo abantu bakora imyitozo ngororamubiri cyangwa imyitozo ngororamubiri, umubiri ukora ROS nyinshi, iyo idakuweho ku gihe, ishobora kwangiza imitsi no kugira ingaruka ku gukira kw'umubiri, mu gihe imikorere ikomeye ya astaxanthin yo kurwanya antioxidant ishobora gukuraho ROS ku gihe no gusana imitsi yangiritse vuba.
Justgood Health yazanye Astaxanthin Complex nshya, ivanzemo magnesium glycerophosphate, vitamine B6 (pyridoxine), na astaxanthin igabanya ububabare bw'imitsi n'umunaniro nyuma yo gukora imyitozo ngororamubiri. Iyi formula ishingiye kuri Whole Algae Complex ya Justgood Health, itanga astaxanthin karemano idakingira imitsi kwangirika kwa oxidative gusa, ahubwo inanoza imikorere y'imitsi no kunoza imikorere y'imikino ngororamubiri.
5) Ubuzima bw'umutima n'imitsi
Imihangayiko ya okisidasiyo n'ububyimbirwe biranga indwara z'umutima n'imitsi ya atherosclerotic. Astaxanthin ifite imikorere myiza cyane ya antioxydants ishobora gukumira no kunoza atherosclerosis.
Justgood Health Triple Strength Natural Astaxanthin Softgels zifasha mu kubungabunga ubuzima bw'umutima n'imitsi binyuze mu gukoresha astaxanthin karemano ikomoka ku mwaro utukura w'umuraba, ibintu by'ingenzi birimo astaxanthin, amavuta ya kokonati y'umwimerere na tocopherols karemano.
6) Kugenzura ubudahangarwa bw'umubiri
Uturemangingo tw’ubudahangarwa bw’umubiri twibasirwa cyane n’ibyangiritse bya free radicals. Astaxanthin irinda ubwirinzi bw’ubudahangarwa bw’umubiri mu gukumira kwangirika kwa free radicals. Ubushakashatsi bwagaragaje ko astaxanthin mu turemangingo tw’abantu kugira ngo ikore immunoglobulines, mu mubiri w’umuntu inyunganiramirire ya astaxanthin mu gihe cy’ibyumweru 8, urugero rwa astaxanthin mu maraso rwiyongereye, uturemangingo twa T na B twiyongereye, kwangirika kwa ADN kuragabanuka, poroteyine ya C-reactive igabanuka cyane.
Astaxanthin softgels, astaxanthin mbisi, ikoresha urumuri rw'izuba karemano, amazi yayunguruwe na lava hamwe n'ingufu z'izuba kugira ngo ikore astaxanthin nziza kandi ifite ubuzima bwiza, ishobora gufasha kongera ubudahangarwa bw'umubiri, kurinda icyerekezo n'ubuzima bw'ingingo.
7) Kugabanya umunaniro
Inyigo y’ibyumweru 4 yakozwe ku buryo bwa “double-blind”, “double-blind”, “placebo-controlled”, “two way crossover” yasanze astaxanthin yateraga gukira umunaniro wo mu mutwe uterwa n’amaso (VDT), ikagabanya urugero rwinshi rwa phosphatidylcholine hydroperoxide (PCOOH) mu gihe cy’imyitozo yo mu mutwe no mu mubiri. Impamvu ishobora kuba ari imikorere ya antioxydant hamwe n’uburyo bwo kurwanya ububyimbirwe bwa astaxanthin.
8) Kurinda umwijima
Astaxanthin igira ingaruka zo gukumira no kugabanya ibibazo by'ubuzima nka fibrosis y'umwijima, imvune yo mu mwijima no kongera gucika intege, na NAFLD. Astaxanthin ishobora kugenzura inzira zitandukanye zo gutanga ibimenyetso, nko kugabanya imikorere ya JNK na ERK-1 kugira ngo yongere ubushobozi bwo kurwanya insuline mu mwijima, kubuza PPAR-γ gukora kugira ngo igabanye imikorere y'ibinure mu mwijima, no kugabanya imikorere ya TGF-β1/Smad3 kugira ngo ihagarike imikorere ya HSCs no fibrosis y'umwijima.
Imiterere y'amabwiriza muri buri gihugu
Mu Bushinwa,astaxanthin Ikomoka ku isoko y'ibimera bitukura by'umukororombya bishobora gukoreshwa nk'ikintu gishya mu biribwa muri rusange (usibye ibiryo by'abana), byongeye kandi, Leta Zunze Ubumwe za Amerika, Kanada n'Ubuyapani nabyo byemerera astaxanthin gukoreshwa mu biribwa.
Igihe cyo kohereza: Ukuboza-05-2024