Astaxanthin (3,3'-dihydroxy-beta, beta-carotene-4,4'-dione) ni karotenoide, ishyirwa mu rwego rwa lutein, iboneka mu binyabuzima bitandukanye ndetse n’inyamaswa zo mu nyanja, kandi mu ntangiriro bitandukanijwe na lobsters na Kuhn na Sorensen. Nibibyibushye byamavuta bigaragara ibara rya orange kugeza umutuku wijimye kandi udafite vitamine A ikora mumubiri wumuntu.
Inkomoko karemano ya astaxanthin irimo algae, umusemburo, salmon, trout, krill na crayfish. Ubucuruzi bwa astaxanthin bukomoka ahanini kumusemburo wa Fife, algae itukura hamwe na synthesis. Imwe mu masoko meza ya astaxantine karemano ni chlorella itukura yimvura, hamwe na astaxantine igera kuri 3.8% (kuburemere bwumye), na salmon yo mwishyamba nayo ni isoko nziza ya astaxantine. Umusaruro wa sintetike uracyari isoko nyamukuru ya astaxanthin kubera igiciro kinini cyo guhinga kwinshi kwa Rhodococcus rainieri. Igikorwa cyibinyabuzima cya astaxantine ikozwe muburyo bwa syntetique ni 50% gusa ya astaxantine karemano.
Astaxanthin ibaho nka stereoisomers, geometrike isomers, imiterere yubuntu kandi yemewe, hamwe na stereoisomers (3S, 3'S) na (3R, 3'R) ninshi muri kamere. Rhodococcus rainieri itanga (3S, 3'S) -isomer na Fife umusemburo utanga (3R, 3'R) -isomer.
Astaxanthin, ubushyuhe bwigihe
Astaxanthin nimwe mu bigize inyenyeri mu biribwa bikora mu Buyapani. Imibare ya FTA ku itangazo ry’ibiribwa bikora mu Buyapani mu 2022 yasanze astaxanthin yashyizwe ku mwanya wa 7 mu bintu 10 byambere mu bijyanye n’inshuro zikoreshwa, kandi yakoreshejwe cyane cyane mu buzima bw’ubuvuzi bw’uruhu, kwita ku maso, kugabanya umunaniro, no kunoza imikorere y’ubwenge.
Muri 2022 na 2023 Ibihembo byintungamubiri zo muri Aziya,Ubuzima bwiza ibinyabuzima bisanzwe bya astaxanthin byamenyekanye nkibintu byiza byumwaka mu myaka ibiri ikurikiranye, icyiza cyiza mumikorere yimikorere ya cognique mumwaka wa 2022, hamwe nibintu byiza mumurongo wubwiza bwo mumunwa mumwaka wa 2023. Byongeye kandi, ibiyigize byashyizwe kurutonde rwibihembo bya Aziya byitwa Nutritional Ingredients Awards - Healthy Aging track in 2024.
Mu myaka yashize, ubushakashatsi bwamasomo kuri astaxanthin nabwo bwatangiye gushyuha. Nk’uko imibare ya PubMed ibigaragaza, nko mu 1948, habaye ubushakashatsi kuri astaxanthin, ariko abantu bakaba baritondeye cyane, guhera mu 2011, ishuri rikuru ryatangiye kwibanda kuri astaxanthin, aho ibitabo bisaga 100 ku mwaka, n'ibirenga 200 muri 2017, birenga 300 muri 2020, birenga 400 muri 2021.
Inkomoko yishusho ： Byatangajwe
Ku bijyanye n’isoko, dukurikije ubushishozi bw’isoko rya Future, ingano y’isoko rya astaxanthin ku isi yose igera kuri miliyoni 273.2 USD mu 2024 bikaba biteganijwe ko izagera kuri miliyoni 665.0 USD muri 2034, kuri CAGR ya 9.3% mu gihe cyateganijwe (2024-2034).
Ubushobozi bwa antioxydeant
Imiterere yihariye ya Astaxanthin itanga imbaraga zidasanzwe za antioxydeant. Astaxanthin ikubiyemo imigozi ibiri, hydroxyl na ketone, kandi ni lipofilique na hydrophilique. Ihuriro ryikubye kabiri hagati yikigo ritanga electron kandi igakora hamwe na radicals yubusa kugirango ihindurwe mubicuruzwa bihamye kandi ihagarike imiyoboro yubusa yibinyabuzima bitandukanye. Igikorwa cyibinyabuzima kiruta icy'izindi antioxydants bitewe nubushobozi bwayo bwo guhuza uturemangingo tuvuye imbere.
Ikibanza cya astaxanthin nizindi antioxydants muri selile
Astaxanthin ikora ibikorwa bikomeye bya antioxydeant binyuze mu gushakisha mu buryo butaziguye radicals yubusa, ahubwo inifashisha uburyo bwo kwirinda antioxydeant selile igenga ibintu bya kirimbuzi erythroide 2 ifitanye isano (Nrf2). Astaxanthin ibuza ishingwa rya ROS kandi ikagenga imvugo ya misemburo ya okiside itera imbaraga, nka heme ogisijene-1 (HO-1), ikaba ari ikimenyetso cyerekana impagarara za okiside.HO-1 igengwa n’ibintu bitandukanye byanduza imitekerereze, harimo na Nrf2, ihuza na antioxydants-yitabira mu karere ka porotokoro.
Urutonde rwuzuye rwa astaxanthin inyungu nibisabwa
1) Kunoza imikorere yubwenge
Ubushakashatsi bwinshi bwemeje ko astaxanthin ishobora gutinza cyangwa kunoza defisititike yubwenge ijyanye no gusaza bisanzwe cyangwa guhuza pathophysiologie yindwara zitandukanye zifata ubwonko. Astaxanthin irashobora kurenga inzitizi yubwonko bwamaraso, kandi ubushakashatsi bwerekanye ko astaxantine yimirire yegeranya muri hippocampus na cerebral cortex yubwonko bwimbeba nyuma yo kuyifata inshuro imwe, bishobora kugira ingaruka kumikorere no kunoza imikorere yubwenge. Astaxanthin iteza imbere ingirabuzimafatizo kandi ikongera imiterere ya gene ya proteine glial fibrillary acide (GFAP), poroteyine 2 ifitanye isano na microtubule (MAP-2), ibintu bikomoka mu bwonko bikomoka mu bwonko (BDNF), hamwe na poroteyine 43 (GAP-43), poroteyine zigira uruhare mu gukira ubwonko.
Ubuzima bwa Justgood Ubuzima bwa Astaxanthin, hamwe na Cytisine na Astaxanthin bo mu ishyamba rya Red Algae Rainforest, bifatanyiriza hamwe kunoza imikorere yubwonko bwubwonko.
2) Kurinda Amaso
Astaxanthin ifite ibikorwa bya antioxydeant itesha agaciro molekile ya ogisijeni yubusa kandi ikingira amaso. Astaxanthin ikorana nubundi karotenoide ifasha ubuzima bwamaso, cyane cyane lutein na zeaxanthin. Byongeye kandi, astaxanthin yongerera umuvuduko w'amaraso gutembera mu jisho, bigatuma amaraso yongera gukora retina na tissue y'amaso. Ubushakashatsi bwerekanye ko astaxanthin, ifatanije nizindi karotenoide, irinda amaso kwangirika kwizuba. Byongeye kandi, astaxanthin ifasha kugabanya uburibwe bw'amaso n'umunaniro ugaragara.
Justgood Ubuzima Ubururu bwo Kurinda Softgels, Ibyingenzi: lutein, zeaxanthin, astaxanthin.
3) Kwita ku ruhu
Guhangayikishwa na Oxidative nimpamvu ikomeye yo gusaza kwuruhu rwabantu no kwangirika kwa dermal. Uburyo bwo gusaza bwimbere (chronologie) hamwe nubusaza (urumuri) ni umusaruro wa ROS, imbere binyuze muri metabolisme ya okiside, ndetse no hanze binyuze mumirasire yizuba ultraviolet (UV). Ibintu bya Oxidative mu gusaza kwuruhu harimo kwangirika kwa ADN, ibisubizo bitera umuriro, kugabanya antioxydants, no gukora matrix metalloproteinase (MMPs) itesha agaciro kolagen na elastine muri dermisi.
Astaxanthin irashobora guhagarika neza kwangirika kwa okiside yubusa no kwinjiza MMP-1 muruhu nyuma yo guhura na UV. Ubushakashatsi bwerekanye ko astaxanthine ikomoka kuri Erythrocystis umukororombya ushobora kongera ibintu bya kolagen mu guhagarika imvugo ya MMP-1 na MMP-3 muri fibroblast ya dermal yumuntu. Byongeye kandi, astaxanthin yagabanije kwangiza ADN iterwa na UV kandi yongera gusana ADN mu ngirabuzimafatizo zangiza imirasire ya UV.
Ubuzima bwa Justgood kuri ubu burimo gukora ubushakashatsi butandukanye, harimo imbeba zitagira umusatsi ndetse n’ibigeragezo byabantu, byose byagaragaje ko astaxanthin igabanya kwangirika kwa UV ku bice byimbitse byuruhu, ibyo bikaba bitera ibimenyetso byerekana gusaza kwuruhu, nko gukama, uruhu runyeganyega hamwe n’iminkanyari.
4) Imirire ya siporo
Astaxanthin irashobora kwihutisha gusana nyuma yimyitozo. Iyo abantu bakora siporo cyangwa imyitozo, umubiri utanga ROS nyinshi, iyo, iyo idakuweho mugihe, ishobora kwangiza imitsi kandi ikagira ingaruka kumubiri, mugihe imikorere ikomeye ya antaxidant ya astaxanthin irashobora gukuraho ROS mugihe kandi igasana imitsi yangiritse vuba.
Ubuzima bwa Justgood butangiza uruganda rwarwo rwa Astaxanthin, ruvanze na magnesium glycerophosphate, vitamine B6 (pyridoxine), na astaxanthin igabanya ububabare bwimitsi n'umunaniro nyuma yo gukora siporo. Amata yibanze kuri Justgood Health's Whole Algae Complex, itanga astaxantine karemano idakingira imitsi kwangirika kwa okiside gusa, ahubwo inongera imikorere yimitsi kandi inoza imikorere yimikino.
5) Ubuzima bwumutima
Guhangayikishwa na Oxidative hamwe no gutwika biranga pathophysiologie yindwara yumutima nimiyoboro y'amaraso. Igikorwa cyiza cyane cya antioxydeant ya astaxanthin irashobora gukumira no kunoza aterosklerose.
Justgood Health Triple Strength Natural Astaxanthin Softgels ifasha kubungabunga ubuzima bwumutima nimiyoboro yimitsi ukoresheje astaxantine karemano ikomoka kumyororokere itukura ya algae itukura, ibyingenzi byingenzi birimo astaxanthine, amavuta yintoki za cocout na tocopherol naturel.
6) Amabwiriza agenga ubudahangarwa
Ingirabuzimafatizo ya sisitemu irumva cyane kwangirika kwubusa. Astaxanthin irinda sisitemu yumubiri kurinda ibyangiritse byubusa. Ubushakashatsi bwerekanye ko astaxantine mu ngirabuzimafatizo z'umuntu kugirango ikore immunoglobuline, mu mubiri w'umuntu wongeyeho astaxanthin mu byumweru 8, urugero rwa astaxantine mu maraso rwiyongereye, selile T na selile B byiyongera, kwangirika kwa ADN kugabanuka, poroteyine C-reaction iragabanuka cyane.
Amashanyarazi ya Astaxanthin, astaxantine mbisi, koresha urumuri rwizuba rusanzwe, amazi yungurujwe na lava ningufu zizuba kugirango bitange astaxantine yera kandi ifite ubuzima bwiza, ishobora gufasha kongera ubudahangarwa, kurinda icyerekezo nubuzima bufatanije.
7) Kuraho umunaniro
Icyumweru 4 cyateganijwe, gihumye-gihumye, kigenzurwa na platbo, inzira ebyiri zambukiranya ubushakashatsi bwerekanye ko astaxanthin yateje imbere gukira kwerekanwa ryerekanwa (VDT) ryatewe n'umunaniro wo mu mutwe, bigatuma plasma fosifatiqueylcholine hydroperoxide (PCOOH) ikomeza mu rwego rwo mu mutwe no mu mubiri. Impamvu irashobora kuba ibikorwa bya antioxydeant hamwe nuburyo bwo kurwanya inflammatory ya astaxanthin.
8) Kurinda umwijima
Astaxanthin ifite ingaruka zo gukumira no gukiza ibibazo byubuzima nka fibrosis yumwijima, gukomeretsa umwijima ischemia-reperfusion, na NAFLD. Astaxanthin irashobora kugena inzira zitandukanye zerekana ibimenyetso, nko kugabanya ibikorwa bya JNK na ERK-1 kugirango tunoze insuline irwanya hepatike, kubuza imvugo ya PPAR-γ kugabanya ibinure byamavuta ya hepatike, no kugabanya imvugo ya TGF-β1 / Smad3 kugirango ibuze gukora HSCs na fibrosis yumwijima.
Imiterere y'amabwiriza muri buri gihugu
Mu Bushinwa,astaxanthin biva mu isoko y'umukororombya algae itukura irashobora gukoreshwa nk'ibiribwa bishya mu biribwa rusange (usibye ibiryo by'abana), hiyongereyeho, Amerika, Kanada n'Ubuyapani na byo byemerera astaxanthin gukoreshwa mu biryo.
Igihe cyo kohereza: Ukuboza-05-2024